Application | Comment | Organism |
---|---|---|
medicine | the structure of gp144 might be useful for the development of new antibacterial reagents for preventing and treating Pseudomonas aeruginosa infections | Phikzvirus phiKZ |
Cloned (Comment) | Organism |
---|---|
into the pQE-30 vector for expression in Escherichia coli cells | Phikzvirus phiKZ |
Crystallization (Comment) | Organism |
---|---|
the x-ray structure of the lytic transglycosylase gp144 is determined to 2.5 A resolution, in complex with chitotetraose, (N-acetylglucosamine)4, to 2.6 A resolution | Phikzvirus phiKZ |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28800 | - |
calculated molecular mass | Phikzvirus phiKZ |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Phikzvirus phiKZ | cleaves the glycosidic linkage between N-acetylmuramoyl and N-acetylglucosaminyl residues | additional information | formation of a 1,6-anhydromuramoyl product | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Phikzvirus phiKZ | Q8SD18 | Pseudomonas bacteriophage | - |
Purification (Comment) | Organism |
---|---|
using a HisTrap HP column | Phikzvirus phiKZ |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cleaves the glycosidic linkage between N-acetylmuramoyl and N-acetylglucosaminyl residues | Phikzvirus phiKZ | additional information | formation of a 1,6-anhydromuramoyl product | ? |
Synonyms | Comment | Organism |
---|---|---|
gp144 | - |
Phikzvirus phiKZ |
phiKZ endolysin | - |
Phikzvirus phiKZ |
transglycosylase | - |
Phikzvirus phiKZ |