Literature summary for 3.2.1.108 extracted from

Tanaka, T.; Suzuki, A.; Kuranuki, S.; Mochizuki, K.; Suruga, K.; Takase, S.; Goda, T.
Higher expression of jejunal LPH gene in rats fed the high-carbohydrate/low-fat diet compared with those fed the low-carbohydrate/high-fat diet is associated with in vitro binding of Cdx-2 in nuclear proteins to its promoter regions (2008), Life Sci., 83, 122-127.

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Cloned(Commentary)

Cloned (Comment)	Organism
higher lactase activity and expression of LPH gene in jejunum of rat fed the high-carbohydrate/low-fat (HCT) diet compared with those fed a lowcarbohydrate/high-fat (LCT) diet is regulated at the transcription levels (nuclear run-on assay). In vitro binding of Cdx-2 to CE-LPH1 gene sequence as well as to SIF1 gene sequence is greater in rats fed a HCT diet than those fed a LCT diet	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	Sprague-Dawley rat	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
jejunum	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
lactose + H2O	-	Rattus norvegicus	D-glucose + D-galactose	-	?

Synonyms

Synonyms	Comment	Organism
lactase-phlorizin hydrolase	-	Rattus norvegicus
LPH	-	Rattus norvegicus

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Release 2023.1 (January 2023)