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Literature summary for 3.2.1.108 extracted from

  • Bueller, H.A.; Kothe, M.J.C.; Goldman, D.A.; Grubman, S.A.; Sasak, W.V.; Matsudaira, P.T.; Montgomery, R.K.; Grand, R.J.
    Coordinate expression of lactate-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development (1990), J. Biol. Chem., 265, 6978-6953.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
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 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus total lactase activity increases to reach maximal levels around weaning, and remains high subsequently, enzyme activity appears to be regulated during development predominantly by transcription mechanism, while alterations during lactation, and along the proximal to distal gradient, are the result of other control mechanism ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
small intestine enzyme activity appears to be regulated during development predominantly by transcription mechanism, while alterations during lactation, and along the proximal to distal gradient, are the result of other control mechanism Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lactose + H2O
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 Rattus norvegicus D-glucose + D-galactose
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 ?
additional information total lactase activity increases to reach maximal levels around weaning, and remains high subsequently, enzyme activity appears to be regulated during development predominantly by transcription mechanism, while alterations during lactation, and along the proximal to distal gradient, are the result of other control mechanism Rattus norvegicus ?
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 ?