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Literature summary for 3.1.6.8 extracted from

  • Takakusaki, Y.; Hisayasu, S.; Hirai, Y.; Shimada, T.
    Coexpression of formylglycine-generating enzyme is essential for synthesis and secretion of functional arylsulfatase A in a mouse model of metachromatic leukodystrophy (2005), Hum. Gene Ther., 16, 929-936.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in arylsulfatase A-deficient mice, HEK-293 cells, HeLa cells and COS-7 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
plasmid encoding human arylsulfatase A was expressed in arylsulfatase A-deficient mice, HEK-293 cells, HeLa cells and COS-7 cells
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
in HEK-293 cells, HeLa cells and COS-7 cells specific activity significantly increased when co-expressed with formylglycine-generating enzyme Homo sapiens
0.0018
-
in serum Homo sapiens
0.0039
-
in liver Homo sapiens
0.0148
-
arylsulfatase A co-expressed with formylglycine-generating enzyme, in liver Homo sapiens
0.0272
-
arylsulfatase A co-expressed with formylglycine-generating enzyme, in serum Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-nitrocatechol sulfate + H2O
-
Homo sapiens p-nitrocatechol + sulfate
-
?

Synonyms

Synonyms Comment Organism
arylsulfatase A
-
Homo sapiens