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Literature summary for 3.1.6.8 extracted from

  • Waheed, A.; Van Etten, R.L.
    Chemical characterization and substrate specificity of rabbit liver aryl sulfatase A (1980), Biochim. Biophys. Acta, 614, 92-101.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.06
-
cerebroside 3-sulfate in presence of 10 mM sodium formate Oryctolagus cuniculus
0.35
-
p-nitrocatechol sulfate
-
Oryctolagus cuniculus
3
-
p-nitrophenol sulfate
-
Oryctolagus cuniculus
4
-
4-methylumbelliferone sulfate
-
Oryctolagus cuniculus
15.9
-
1-naphthyl sulfate
-
Oryctolagus cuniculus
31.8
-
Tyrosine O-sulfate
-
Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Oryctolagus cuniculus 5764
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
zonal and frontal gel filtration Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cerebroside 3-sulfate + H2O Oryctolagus cuniculus
-
cerebroside + sulfate
-
?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein liver: 4.6% carbohydrate Oryctolagus cuniculus

Purification (Commentary)

Purification (Comment) Organism
-
Oryctolagus cuniculus

Reaction

Reaction Comment Organism Reaction ID
a cerebroside 3-sulfate + H2O = a cerebroside + sulfate hydrolyses galactose-3-sulfate residues in a number of lipids, also hydrolyses ascorbate 2-sulfate and many phenol sulfates, enzymes catalyze in addition to reaction of EC 3.1.6.8 also arylsulfatase reaction EC 3.1.6.1 Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthyl sulfate + H2O
-
Oryctolagus cuniculus 1-naphthol + sulfate
-
?
4-nitrophenyl sulfate + H2O
-
Oryctolagus cuniculus 4-nitrophenol + sulfate
-
?
ascorbate 2-sulfate + H2O
-
Oryctolagus cuniculus ascorbate + sulfate
-
?
cerebroside 3-sulfate + H2O
-
Oryctolagus cuniculus cerebroside + sulfate
-
?
dehydroisoandrosterone sulfate + H2O
-
Oryctolagus cuniculus dehydroisoandrosterone + sulfate
-
?
estriol 3-sulfate + H2O
-
Oryctolagus cuniculus estriol + sulfate
-
?
estrone 3-sulfate + H2O
-
Oryctolagus cuniculus estrone + sulfate
-
?
methylumbelliferyl sulfate + H2O
-
Oryctolagus cuniculus methylumbelliferone + sulfate
-
?
nitrocatechol sulfate + H2O
-
Oryctolagus cuniculus nitrocatechol + sulfate
-
?
tyrosine O-sulfate + H2O
-
Oryctolagus cuniculus tyrosine + sulfate
-
?

Subunits

Subunits Comment Organism
monomer 1 * 140000, each monomer consists of 2 equivalent polypeptide chains Oryctolagus cuniculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay Oryctolagus cuniculus