Application | Comment | Organism |
---|---|---|
medicine | in humans, the inherited deficiency of the enzyme activity results in mucopolysaccharidosis type II, the Hunter syndrome | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of identified mutations in COS 7 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | K347T, N265I, 473delTCC, 533delTT mutations are identified in four out of 28 Hunter syndrome patients | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
x * 55000, Western blot analysis, wild-type enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is responsible for heparin sulfate and dermatan sulfate degradation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is responsible for heparin sulfate and dermatan sulfate degradation | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 55000, Western blot analysis, wild-type enzyme | Homo sapiens |