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Literature summary for 3.1.6.13 extracted from

  • Constantopoulos, G.; Rees, S.; Cragg, B.G.; Barranger, J.A.; Brady, R.O.
    Experimental animal model for mucopolysaccharidosis: suramin-induced glycosaminoglycan and sphingolipid accumulation in the rat (1980), Proc. Natl. Acad. Sci. USA, 77, 3700-3704.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.6.13

Application

Application Comment Organism
medicine animal model for mucopolysaccharidosis Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
suramin in vivo and in vitro Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Rattus norvegicus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dermatan sulfate + H2O Rattus norvegicus
-
 dermatan + sulfate
-
 ?
heparan sulfate + H2O Rattus norvegicus
-
 dermatan + sulfate
-
 ?
heparin + H2O Rattus norvegicus
-
 desulfated heparin + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dermatan sulfate + H2O
-
 Rattus norvegicus dermatan + sulfate
-
 ?
heparan sulfate + H2O
-
 Rattus norvegicus dermatan + sulfate
-
 ?
heparin + H2O
-
 Rattus norvegicus desulfated heparin + sulfate
-
 ?