Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | - |
Homo sapiens | |
citrate | - |
Homo sapiens | |
Cl- | at high concentration | Homo sapiens | |
Cu2+ | - |
Homo sapiens | |
Fe3+ | - |
Homo sapiens | |
Hg2+ | - |
Homo sapiens | |
NaCl | inhibits at 10-100 mM | Homo sapiens | |
nitrocatechol sulfate | competitive inhibitor | Homo sapiens | |
Phenolphthalein disulfate | - |
Homo sapiens | |
Zn2+ | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | 0.02 | sulfoiduronyl sulfoanhydromannitol | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparan sulfate + H2O | Homo sapiens | - |
dermatan + sulfate | - |
? | |
heparin + H2O | Homo sapiens | - |
desulfated heparin + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
several molecular species | - |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00083 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
frozen | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dermatan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparan sulfate + H2O | - |
Homo sapiens | dermatan + sulfate | - |
? | |
heparin + H2O | - |
Homo sapiens | desulfated heparin + sulfate | - |
? | |
O-(alpha-L-idopyranosyluronic acid 2-sulfate)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + H2O | - |
Homo sapiens | O-(alpha-L-idopyranosyluronic acid)-(1-4)-2,5-anhydro-D-mannitol 6-sulfate + sulfate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
pH 4.0, 0.1 M sodium acetate, 1% bovine serum albumin, 2 h, 50% inactivation | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4 | - |
precipitous decrease in activity at higher pH | Homo sapiens |