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Literature summary for 3.1.6.1 extracted from
- In vitro effect of schistosomicidal drugs on hepatic arylsulfatase B from the schistosoma-infected mouse (2006), J. Enzyme Inhib. Med. Chem., 21, 81-85.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Commiphora extract | schistosomical drug, activating to enzyme. No effect on immunological properties of enzyme | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| praziquantel | schistosomical drug, inhibitory to enzyme. No effect on immunological properties of enzyme | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
isoform arylsulfatase B, in liver of Schistosoma-infected mouse | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from liver of Schistosoma-infected animal | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | enzyme activity is elevated in mouse schistosomiasis | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrocatechol sulfate + H2O | - |
Mus musculus | 4-nitrocatechol + sulfate | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00055 | - |
praziquantel | pH 6.0, 37°C | Mus musculus | |
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