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Literature summary for 3.1.6.1 extracted from

  • Shapira, E.; Nadler, H.L.
    Purification and some properties of soluble human liver arylsulfatases (1975), Arch. Biochem. Biophys., 170, 179-187.
    View publication on PubMed
Search for more literature for 3.1.6.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8
-
 4-nitrocatechol sulfate arylsulfatase A Homo sapiens
2.9
-
 4-nitrocatechol sulfate arylsulfatase B Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51000
-
 arylsulfatase B, gel filtration Homo sapiens
107000
-
 arylsulfatase A, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
arylsulfatase A and B Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.07
-
 arylsulfatase B Homo sapiens
4.82
-
 arylsulfatase A Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrocatechol sulfate + H2O
-
 Homo sapiens 4-nitrocatechol + sulfate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.2
-
 arylsulfatase A Homo sapiens
5.6
-
 arylsulfatase B Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
4 6 pH 4: about 35% of maximal activity, pH 6.0: about 75% of maximal activity Homo sapiens
4 6 about 45% maximal activity at pH 4 and pH 6, arylsulfatase A Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
4
-
 below pH 4 in presence of 1% SDS arylsulfatase A is irreversibly converted into inactive subunits Homo sapiens