Cloned (Comment) | Organism |
---|---|
- |
Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-isobutyl-1-methylxanthine | - |
Trypanosoma cruzi | |
dipyridamole | - |
Trypanosoma cruzi | |
erythro-9-(2-hydroxy-3-nonyl)-adenine hydrochloride | - |
Trypanosoma cruzi | |
papaverine | - |
Trypanosoma cruzi | |
rolipram | - |
Trypanosoma cruzi | |
vinpocetine | - |
Trypanosoma cruzi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0073 | - |
adenosine 3',5'-cyclic phosphate | - |
Trypanosoma cruzi |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
flagellum | - |
Trypanosoma cruzi | - |
- |
plasma membrane | - |
Trypanosoma cruzi | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | activity was higher in the presence of Mn2+ than Mg2+ as cofactor | Trypanosoma cruzi | |
Mn2+ | activity was higher in the presence of Mn2+ than Mg2+ as cofactor | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | Q6XG56 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine 3',5'-cyclic phosphate + H2O | - |
Trypanosoma cruzi | adenosine 5'-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cAMP-specific phosphodiesterase | - |
Trypanosoma cruzi |
TcPDE1 | - |
Trypanosoma cruzi |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.017 | - |
- |
Trypanosoma cruzi | dipyridamole | |
0.111 | - |
- |
Trypanosoma cruzi | papaverine | |
0.134 | - |
- |
Trypanosoma cruzi | vinpocetine | |
0.217 | - |
- |
Trypanosoma cruzi | erythro-9-(2-hydroxy-3-nonyl)-adenine hydrochloride |