Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Co2+ | extracellular enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | extracellular enzyme | Homo sapiens | |
ATP | extracellular enzyme | Homo sapiens | |
Cu2+ | the inhibition of extracellular enzyme can be prevented by 2,6-di-tert-butyl-4-hydroxy-methylphenol | Rattus norvegicus | |
EDTA | extracellular enzyme | Homo sapiens | |
EDTA | inhibition of extracellular enzyme | Rattus norvegicus | |
p-hydroxymercuribenzoate | the inhibition of the microsomal enzyme can be prevented by glutathione and dithiothreitol | Rattus norvegicus | |
serine esterase inhibitors | inhibition of extracellular enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
extracellular | - |
Rattus norvegicus | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Oryctolagus cuniculus | |
Ca2+ | microsomal enzyme | Rattus norvegicus | |
Co2+ | extracellular enzyme | Rattus norvegicus | |
Mg2+ | low effect in rabbit kidney | Oryctolagus cuniculus | |
Mg2+ | microsomal enzyme | Rattus norvegicus | |
Mn2+ | extracellular enzyme | Rattus norvegicus | |
Ni2+ | extracellular enzyme | Rattus norvegicus | |
Zn2+ | extracellular enzyme | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the product lysophosphatidic acid mediates multiple biological functions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Oryctolagus cuniculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | medium of cultured adipocytes | Homo sapiens | - |
brain | - |
Rattus norvegicus | - |
epithelial cell | - |
Rattus norvegicus | - |
gastric mucosa | - |
Rattus norvegicus | - |
kidney | - |
Oryctolagus cuniculus | - |
liver | - |
Rattus norvegicus | - |
plasma | - |
Homo sapiens | - |
plasma | - |
Rattus norvegicus | - |
plasma | - |
Oryctolagus cuniculus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-alkyl-sn-glycero-3-phosphocholine + H2O | - |
Rattus norvegicus | 1-alkyl-sn-glycero-3-phosphate + choline | - |
? | |
1-O-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + H2O | the microsomal enzyme | Rattus norvegicus | 1-O-alkyl-2-lyso-sn-glycero-3-phosphate + ethanolamine | the microsomal enzyme | ? | |
additional information | the microsomal enzymes prefer alkyl-lysophospholipids, the extracellular enzyme prefer acyl-phospholipids, but can use alkyl-lysophospholipids | Rattus norvegicus | ? | - |
? | |
additional information | the plasma enzyme hydrolyzes acyl-, alkyl- and alkenyl-lysophophatidylcholines | Homo sapiens | ? | - |
? | |
additional information | the product lysophosphatidic acid mediates multiple biological functions | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | molecular identity of autotoxin and enzyme | Homo sapiens |