Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.4.14 extracted from

  • Sobhy, C.
    Regulation of fatty acid synthetase activity. The 4'-phosphopantetheine hydrolase of rat liver (1979), J. Biol. Chem., 254, 8561-8566.
    View publication on PubMed
Search for more literature for 3.1.4.14

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol required Rattus norvegicus
dithiothreitol required Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required, or other divalent cations Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
1 mol holo-fatty acid synthetase contains 1 mol 4'-phosphopantetheine Rattus norvegicus
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining

Storage Stability

Storage Stability Organism
-20oC, under nitrogen, dithiothreitol or 2-mercaptoethanol, long periods, no loss of activity Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
holo-fatty acid synthetase + H2O no activity on coenzyme A Rattus norvegicus apo-fatty acid synthetase + 4'-phosphopantetheine
-
 ?
holo-fatty acid synthetase + H2O 1 mol holo-fatty acid synthetase contains 1 mol 4'-phosphopantetheine Rattus norvegicus apo-fatty acid synthetase + 4'-phosphopantetheine
-
 ?
holo-fatty acid synthetase + H2O specific for rat liver holo-fatty acid synthetase, no activity on pigeon liver holo-fatty acid synthetase Rattus norvegicus apo-fatty acid synthetase + 4'-phosphopantetheine
-
 ?

Synonyms

Synonyms Comment Organism
4'-phosphopantetheine hydrolase
-
 Rattus norvegicus
holofatty acid synthetase hydrolase
-
 Rattus norvegicus