Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidylinositol + H2O | - |
Rattus norvegicus | 1D-myo-inositol 1-phosphate + diacylglycerol | in vitro also 1D-myo-inositol 1,2-cyclic phosphate formed | ? |
Synonyms | Comment | Organism |
---|---|---|
phosphatidylinositol phosphodiesterase | phospholipase C-type | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
assay at | Rattus norvegicus |
5.6 | - |
when (NH4)2SO4 fractionation (30-50%) of the brain supernatant is carried out, the phosphodiesterase preparation obtained shows an optimum at pH 5.6 | Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5 | 8.5 | - |
Rattus norvegicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Rattus norvegicus | 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 | 4.2 | 3.8 |
Rattus norvegicus | 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 | 4.8 | 4.4 |
Rattus norvegicus | when assayed at pH 7.0 and pH 8.0, 1 mM Ca2+ | - |
4.6 |
Rattus norvegicus | 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 | - |
5.86 |
Rattus norvegicus | 4 peaks of phosphodiesterase activity are found at pl ranges 7.2-7.4 , 5.8-6.0, 4.4-4.8 and 3.8-4.2, pH 5.5 | 7.4 | 7.2 |