Protein Variants | Comment | Organism |
---|---|---|
G129E | mutant enzyme is selectively deficient in the lipid phosphatase activity but still blocks the cell cycle of MCF-7 cells | Homo sapiens |
H123Y | mutant enzyme lacking phosphatase activity is ineffective in blocking the cell cycle of MCF-7 cells | Homo sapiens |
H129R | mutant enzyme lacking phosphatase activity is ineffective in blocking the cell cycle of MCF-7 cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | protein phosphatase activity may contribute to the cell cycle inhibitory and thereby tumor suppresive function of PTEN | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell line | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | protein phosphatase activity may contribute to the cell cycle inhibitory and thereby tumor suppresive function of PTEN | Homo sapiens | ? | - |
? |