Application | Comment | Organism |
---|---|---|
pharmacology | inhibitors could be used to diminish nucleotide depletion during ischemia/reperfusion | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R,4S,5R)-1-[5-(2-fluoro-2-phosphonoethyl)tetrahydro-4-hydroxy-2-furyl]thymine | - |
Oryctolagus cuniculus | |
(2R,4S,5R)-1-[tetrahydro-4-hydroxy-5-(2-phosphonoethyl)-2-furyl]thymine | - |
Oryctolagus cuniculus | |
(2R,5R)-1-[5-(2-fluoro-2-phosphonoethyl)tetrahydro-2-furyl]thymine | - |
Oryctolagus cuniculus | |
(2R,5S)-1-[tetrahydro-5-(2-phosphonoethyl)-2-furyl]thymine | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
5'-TMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
0.061 | - |
5'-dCMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
0.11 | - |
5'-CMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
0.13 | - |
5'-dAMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
0.32 | - |
5'-GMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
1 | - |
5'-IMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus | |
1.2 | - |
5'-AMP | cytosolic enzyme c-N-I | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Oryctolagus cuniculus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
10 | - |
enzyme e-N | Oryctolagus cuniculus |
71 | - |
enzyme c-N-I | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | - |
Oryctolagus cuniculus | adenosine + phosphate | - |
? | |
5'-CMP + H2O | - |
Oryctolagus cuniculus | cytidine + phosphate | - |
? | |
5'-dAMP + H2O | i.e. 2'-deoxyadenosine 5'-phosphate | Oryctolagus cuniculus | deoxyadenosine + phosphate | - |
? | |
5'-dCMP + H2O | i.e. 2'-deoxycytosine 5'-phosphate | Oryctolagus cuniculus | deoxycytidine + phosphate | - |
? | |
5'-dGMP + H2O | i.e. 2'-deoxyguanosine 5'-phosphate | Oryctolagus cuniculus | deoxyguanosine + phosphate | - |
? | |
5'-GMP + H2O | - |
Oryctolagus cuniculus | guanosine + phosphate | - |
? | |
5'-IMP + H2O | - |
Oryctolagus cuniculus | inosine + phosphate | - |
? | |
5'-TMP + H2O | - |
Oryctolagus cuniculus | thymidine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
c-N-II | - |
Oryctolagus cuniculus |
cN-I | - |
Oryctolagus cuniculus |
e-N | - |
Oryctolagus cuniculus |