Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ammonium molybdate | - |
Tritrichomonas suis | |
additional information | no inhibition of the enzyme by phosphatase inhibitors. i.e. sodium orthovanadate and sodium fluoride | Tritrichomonas suis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Michaelis-Menten kinetics | Tritrichomonas suis | |
0.49 | - |
5'-AMP | pH 7.2, 36°C | Tritrichomonas suis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | plasma membrane-bound ecto-enzyme activity | Tritrichomonas suis | 9986 | - |
extracellular | plasma membrane-bound ecto-enzyme activity | Tritrichomonas suis | - |
- |
plasma membrane | plasma membrane-bound ecto-enzyme activity | Tritrichomonas suis | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | Mg2+, Mn2+, Sr2+, or Ca2+, as well as the metal chelators EGTA or EDTA, have no effect on the ecto-5'-nucleotidase activity | Tritrichomonas suis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | Tritrichomonas suis | - |
adenosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tritrichomonas suis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | - |
Tritrichomonas suis | adenosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CD73 | - |
Tritrichomonas suis |
ecto-5'-nucleotidase | - |
Tritrichomonas suis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
36 | - |
assay at | Tritrichomonas suis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Tritrichomonas suis |
General Information | Comment | Organism |
---|---|---|
metabolism | Trichomonas foetus is devoid of the ability to synthesize purine nucleotides de novo, depending instead on salvaging purines from the host environment. Ecto-5'-nucleotidase catalyzes the final step of extracellular nucleotide degradation, the hydrolysis of nucleoside 5'-monophosphates to the corresponding nucleosides and phosphate | Tritrichomonas suis |