Cloned (Comment) | Organism |
---|---|
recombinant expression in COS-7 cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha,beta-methylene-ADP | a specific CD73 inhibitor | Mus musculus | |
alpha/beta-methylene-ADP | a specific CD73 inhibitor | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | Mus musculus | - |
adenosine + phosphate | - |
? | |
5'-AMP + H2O | Rattus norvegicus | - |
adenosine + phosphate | - |
? | |
5'-AMP + H2O | Mus musculus C57BL/6 | - |
adenosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus C57BL/6 | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epididymis | - |
Mus musculus | - |
epithelial cell | secretory epithelia from exocrine glands | Mus musculus | - |
germ cell | - |
Mus musculus | - |
interstitial cell | - |
Mus musculus | - |
peritubular cell | - |
Mus musculus | - |
reproductive system | - |
Mus musculus | - |
Sertoli cell | - |
Mus musculus | - |
smooth muscle cell | - |
Mus musculus | - |
somatic cell | - |
Mus musculus | - |
testis | high enzyme level. Ecto-5'-nucleotidase is immunolocalized in testes, in association with germinal cells along all stages of spermatogenesis, but not in spermatozoa | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | - |
Mus musculus | adenosine + phosphate | - |
? | |
5'-AMP + H2O | - |
Rattus norvegicus | adenosine + phosphate | - |
? | |
5'-AMP + H2O | - |
Mus musculus C57BL/6 | adenosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ecto-5'-nucleotidase/CD73 | - |
Mus musculus |
ecto-5'-nucleotidase/CD73 | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |
7.4 | - |
assay at | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme plays a role in the generation of extracellular adenosine, a key modulator of male fertility | Mus musculus |
physiological function | the enzyme plays a role in the generation of extracellular adenosine, a key modulator of male fertility | Rattus norvegicus |