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Literature summary for 3.1.3.5 extracted from

  • Wang, L.; Zhou, X.; Zhou, T.; Ma, D.; Chen, S.; Zhi, X.; Yin, L.; Shao, Z.; Ou, Z.; Zhou, P.
    Ecto-5'-nucleotidase promotes invasion, migration and adhesion of human breast cancer cells (2008), J. Cancer Res. Clin. Oncol., 134, 365-372.
    View publication on PubMed

Application

Application Comment Organism
medicine CD73 may facilitate the adhesion, migration, and invasion of human breast cancer cells through its enzyme activity of generating adenosine Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
adenosine 5'-(alpha,beta-methylene)diphosphate
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O best substrate Homo sapiens adenosine + phosphate
-
?

Synonyms

Synonyms Comment Organism
5'-NT
-
Homo sapiens
CD73
-
Homo sapiens
ecto 5'-nucleotidase
-
Homo sapiens
ecto-5-NT
-
Homo sapiens