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Literature summary for 3.1.3.5 extracted from

  • Dhananjaya, B.L.; Nataraju, A.; Rajesh, R.; Raghavendra Gowda, C.D.; Sharath, B.K.; Vishwanath, B.S.; DSouza, C.J.
    Anticoagulant effect of Naja naja venom 5'-nucleotidase: demonstration through the use of novel specific inhibitor, vanillic acid (2006), Toxicon, 48, 411-421.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
concanavalin A complete inhibition at 0.006 mM Naja naja
vanillic acid competitive inhibitor, complete inhibition at 0.6 mM Naja naja

Organism

Organism UniProt Comment Textmining
Naja naja
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Naja naja
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Naja naja adenosine + phosphate
-
 ?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0024
-
 in 50 mM Tris-HCl buffer, pH 7.4, 10 mM MgCl2, 50 mM NaCl, 10 mM KCl, at 37°C Naja naja concanavalin A
0.18
-
 in 50 mM Tris-HCl buffer, pH 7.4, 10 mM MgCl2, 50 mM NaCl, 10 mM KCl, at 37°C Naja naja vanillic acid