Literature summary for 3.1.3.5 extracted from

Pedrazza, E.L.; Senger, M.R.; Rico, E.P.; Zimmermann, F.F.; Pedrazza, L.; de Freitas Sarkis, J.J.; Bonan, C.D.
Fluoxetine and nortriptyline affect NTPDase and 5'-nucleotidase activities in rat blood serum (2007), Life Sci., 81, 1205-1210.

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Inhibitors

Inhibitors	Comment	Organism	Structure
fluoxetine	chronic treatment with 10mg/kg fluoxetine causes a 42% inhibition of AMP hydrolysis	Rattus norvegicus
additional information	in vitro and short-term in vivo treatment with fluoxetine and nortriptyline causes no change in activity	Rattus norvegicus
nortriptyline	chronic treatment with 10mg/kg nortriptyline causes a 30% inhibition of AMP hydrolysis	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Rattus norvegicus	adenosine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
ecto-5'-nucleotidase	-	Rattus norvegicus

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Release 2023.1 (January 2023)