Cloned (Comment) | Organism |
---|---|
expressed in K-562 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D182A | inactive | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by H2O2 treatment | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P17706 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | does not dephosphorylate c-Abl | Homo sapiens | ? | - |
? | |
phosphorylated BCR-Abl + H2O | - |
Homo sapiens | BCR-Abl + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TC48 | isoform | Homo sapiens |
TCPTP | - |
Homo sapiens |
tyrosine phosphatase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform TC48 inhibits proliferation and enhances sensitivity of K562 cells to STI571 | Homo sapiens |