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Literature summary for 3.1.3.48 extracted from

  • Maksumova, L.; Le, H.T.; Muratkhodjaev, F.; Davidson, D.; Veillette, A.; Pallen, C.J.
    Protein tyrosine phosphatase alpha regulates Fyn activity and Cbp/PAG phosphorylation in thymocyte lipid rafts (2005), J. Immunol., 175, 7947-7956.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information in thymocytes of enzyme-deficient animal, cells develop normally, but show increased tyrosine phosphorylation of specific proteins, increased Fyn activity due to enhanced phosphorylation of Y528 and Y417, and hyperphosphorylation of Cbp/PAG Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus protein tyrosine phosphatase alpha regulates the activity of raft Fyn ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
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isoform protein tyrosine phosphatase alpha, enzyme-deficinet animal
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Source Tissue

Source Tissue Comment Organism Textmining
thymocyte of enzyme-deficient animal, cells develop normally, but show increased tyrosine phosphorylation of specific proteins, increased Fyn activity due to enhanced phosphorylation of Y528 and Y417, and hyperphosphorylation of Cbp/PAG Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information protein tyrosine phosphatase alpha regulates the activity of raft Fyn Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
protein tyrosine phosphatase alpha
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Mus musculus