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Literature summary for 3.1.3.4 extracted from

  • Renault, A.D.; Kunwar, P.S.; Lehmann, R.
    Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in Drosophila (2010), Development, 137, 1815-1823.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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-
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Source Tissue

Source Tissue Comment Organism Textmining
embryonic germ cell
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Drosophila melanogaster
-

Synonyms

Synonyms Comment Organism
lipid phosphate phosphatase
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Drosophila melanogaster
LPP
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Drosophila melanogaster
wun
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Drosophila melanogaster
wun2
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Drosophila melanogaster
Wunen
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Drosophila melanogaster

General Information

General Information Comment Organism
malfunction lack of wun2 in germ cells results in germ cell death Drosophila melanogaster
physiological function lipid phosphate phosphatase mediates germ cell-germ cell repulsion, this repulsion is necessary for germ cell dispersal and proper transepithelial migration at the onset of migration and for the equal sorting of the germ cells between the two embryonic gonads during their migration Drosophila melanogaster