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Literature summary for 3.1.3.4 extracted from

  • Fuentes, L.; Perez, R.; Nieto, M.L.; Balsinde, J.; Balboa, M.A.
    Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2 (2003), J. Biol. Chem., 278, 44683-44690.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
bromoenol lactone bromoenol lactone-induced apoptosis is accompanied by a very strong inhibition of PAP-1-regulated events, such as incorporation of choline into phospholipids and de novo incorporation of arachidonic acid into triacylglycerol Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens role of PAP-1 as a key enzyme for cell integrity and survival ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
Homo sapiens
-
phagocyte U937, THP-1 and MonoMac Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information role of PAP-1 as a key enzyme for cell integrity and survival Homo sapiens ?
-
?