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Literature summary for 3.1.3.16 extracted from

  • Chen, J.; Hu, R.; Zhu, Y.; Shen, G.; Zhang, H.
    Arabidopsis thaliana phosphotyrosyl phosphatase activator is essential for protein phosphatase 2A holoenzyme assembly and plays important roles in hormone signaling, salt stress response, and plant development (2014), Plant Physiol., 166, 1519-1534.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
cantharidin
-
 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoprotein + H2O Arabidopsis thaliana
-
 protein + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoprotein + H2O
-
 Arabidopsis thaliana protein + phosphate
-
 ?

Subunits

Subunits Comment Organism
heterotrimer
-
 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
PP2A
-
 Arabidopsis thaliana
protein phosphatase 2A
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana reduced expression of phosphotyrosyl phosphatase activator leads to decreased protein phosphatase 2A (PP2A) activity. In particular, phosphotyrosyl phosphatase activator deficiency leads to decreased methylation in PP2A-C subunits. Complete loss of PP2Ac methylation leads to 30% reduction of PP2A activity down