Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calyculin A | - |
Homo sapiens | |
DARPP-32 | - |
Homo sapiens | |
Inhibitor-2 | - |
Homo sapiens | |
microcystin | - |
Homo sapiens | |
nodularin | - |
Homo sapiens | |
okadaic acid | - |
Homo sapiens | |
tautomycin | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | the catalytic active site contains two Mn2+ ions, Mn2+-bound enzyme always exhibits the highest activity and stability | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38500 | - |
x * 38500, calculated from amino acid sequence | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoprotein + H2O | Homo sapiens | - |
protein + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P62136 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoprotein + H2O | - |
Homo sapiens | protein + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 38500, calculated from amino acid sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PP1 | - |
Homo sapiens |
protein phosphatase 1 | - |
Homo sapiens |
serine/threonine protein phosphatase 1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | PP1 regulates diverse, essential cellular processes such as cell cycle progression, protein synthesis, muscle contraction, carbohydrate metabolism, transcription and neuronal signaling | Homo sapiens |