Literature summary for 3.1.3.16 extracted from

Zhang, M.; Yogesha, S.D.; Mayfield, J.E.; Gill, G.N.; Zhang, Y.
Viewing serine/threonine protein phosphatases through the eyes of drug designers (2013), FEBS J., 280, 4739-4760.

Inhibitors

Inhibitors	Comment	Organism
calyculin A	-	Bos taurus
calyculin A	-	Homo sapiens
cantharidin	-	Bos taurus
cantharidin	-	Homo sapiens
cyclosporin A	-	Bos taurus
cyclosporin A	-	Homo sapiens
FK506	-	Bos taurus
FK506	-	Homo sapiens
fostriecin	-	Bos taurus
fostriecin	-	Homo sapiens
microcystin-LR	-	Bos taurus
microcystin-LR	-	Homo sapiens
okadaic acid	-	Bos taurus
okadaic acid	-	Homo sapiens
phosphonothioic acid	-	Bos taurus
phosphonothioic acid	-	Homo sapiens
sanguinarine	-	Bos taurus
sanguinarine	-	Homo sapiens
tautomycin	-	Bos taurus
tautomycin	-	Homo sapiens

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
phosphoprotein + H2O	Bos taurus	-	protein + phosphate	-	?
phosphoprotein + H2O	Homo sapiens	-	protein + phosphate	-	?

Organism	UniProt	Comment	Textmining
Bos taurus	P48452	catalytic subunit	-
Homo sapiens	P36873	catalytic subunit	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphoprotein + H2O	-	Bos taurus	protein + phosphate	-	?
phosphoprotein + H2O	-	Homo sapiens	protein + phosphate	-	?

Synonyms	Comment	Organism
calcineurin	-	Bos taurus
PP1gamma	-	Homo sapiens
PP2B	isoform	Bos taurus
PP3	-	Bos taurus
protein serine/threonine phosphatase	-	Bos taurus
protein serine/threonine phosphatase	-	Homo sapiens
PSP	-	Bos taurus
PSP	-	Homo sapiens
serine/threonine protein phosphatase	-	Bos taurus
serine/threonine protein phosphatase	-	Homo sapiens

General Information	Comment	Organism
physiological function	isoform PP1 plays critical roles in an enormous variety of cellular processes such as cell cycle progression, protein synthesis, carbohydrate metabolism and apoptosis	Homo sapiens