Literature summary for 3.1.3.16 extracted from

Chen, L.; Dong, W.; Zou, T.; Ouyang, L.; He, G.; Liu, Y.; Qi, Y.
Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6 (2008), FEBS Lett., 582, 2843-2849.

Search for more literature for 3.1.3.16

Activating Compound

Activating Compound	Comment	Organism	Structure
lipopolysaccharide	lipopolysaccharide stimulation induces the expression of PP4	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in HEK-293T cells and RAW264.7 cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	fetal brain	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
tumor necrosis factor receptor-associated factor 6 + H2O	PP4 negatively regulates lipopolysaccharide-induced and tumor necrosis factor receptor-associated factor 6-mediated nuclear factor-kappaB activation by inhibiting the ubiquitination of tumor necrosis factor receptor-associated factor 6, PP4 is a negative feedback regulator of lipopolysaccharide/toll-like receptor 4 pathway	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
Pp4	-	Homo sapiens
protein phosphatase 4	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)