Cloned (Comment) | Organism |
---|---|
expressed in HeLa and HEK-293 cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
440000 | - |
the PP6 catalytic subunit, SAPS domain subunits PP6R1 and PP6R3, and ankyrin repeat subunit ARS-A are all detected by immunoblotting, showing copurification in complexes with apparent Mr values of above 440 kDa | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial purification by DEAE column chromatography and Superose 12 gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoprotein + H2O | - |
Homo sapiens | protein + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotrimer | composed of the PP6 catalytic subunit bound to a suppressor of initiation of transcription 4-associated protein domain scaffold subunit that associates with ankyrin repeat protein 28 | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PP6 | - |
Homo sapiens |
PP6R1 | regulatory subunit of protein phosphatase 6, PP6R1 acts as a scaffold with separate regions for binding to protein phosphatase 6 and to ankyrin repeat protein 28 | Homo sapiens |
protein phosphatase 6 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Homo sapiens |