Inhibitors | Comment | Organism | Structure |
---|---|---|---|
okadaic acid | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the Pro33 isoform of integrin beta3 enhances outside-in signaling in platelets by regulating the activation of serine/threonine phosphatases | ? | - |
? | |
phosphorylated ERK2 + H2O | Homo sapiens | - |
ERK2 + phosphate | - |
? | |
phosphorylated myosin light chain + H2O | Homo sapiens | dephosphorylation at Thr696 | myosin light chain + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate | the enzyme also performs the reaction of EC 3.1.3.53, myosin-light-chain-phosphatase | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | Pro33-isozyme positive platelets show increased MLC and ERK phosphorylation and reduced protein phosphatase activity, and vice versa in Pro33-isozyme negative platelets, overview | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the Pro33 isoform of integrin beta3 enhances outside-in signaling in platelets by regulating the activation of serine/threonine phosphatases | Homo sapiens | ? | - |
? | |
phosphorylated ERK2 + H2O | - |
Homo sapiens | ERK2 + phosphate | - |
? | |
phosphorylated myosin light chain + H2O | dephosphorylation at Thr696 | Homo sapiens | myosin light chain + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | EC 3.1.3.53, myosin-light-chain-phosphatase | Homo sapiens |
serine/threonine phosphatase | - |
Homo sapiens |