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Literature summary for 3.1.3.16 extracted from

  • Hegardt, F.G.
    Regulation of rat liver HMG-CoA reductase by reductase kinase and the cytosolic and microsomal protein phosphatases (1986), Adv. Protein Phosphatases, 3, 1-30.
No PubMed abstract available
Search for more literature for 3.1.3.16

Inhibitors

Inhibitors Comment Organism Structure
3-hydroxy-3-methylglutaryl CoA
-
 Rattus norvegicus
ATP
-
 Rattus norvegicus
citrate
-
 Rattus norvegicus
F-
-
 Rattus norvegicus
NADPH
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Rattus norvegicus 5737
-
microsome phosphatase IIm Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Rattus norvegicus
Co2+
-
 Rattus norvegicus
Mg2+
-
 Rattus norvegicus
Mn2+ activation Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoprotein + H2O Rattus norvegicus control of cholesterol genesis protein + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
2 forms Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphophosphorylase kinase + H2O specific for alpha-subunit Rattus norvegicus phosphorylase kinase + phosphate
-
 ?
phosphoprotein + H2O control of cholesterol genesis Rattus norvegicus protein + phosphate
-
 ?
phosphoproteins + H2O
-
 Rattus norvegicus proteins + phosphate
-
 ?
phosphorylated 3-hydroxy 3-methylglutaryl coenzyme A reductase + H2O
-
 Rattus norvegicus 3-hydroxy 3-methylglutaryl coenzyme A reductase + phosphate
-
 ?