Literature summary for 3.1.3.1 extracted from

Chakraborty, S.; Asgeirsson, B.; Minda, R.; Salaye, L.; Frere, J.M.; Rao, B.J.
Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-beta-lactamase active sites (2012), FEBS Lett., 586, 3710-3715.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Imipenem	inhibition is time dependent reaching about 98% in 30 min on ice at 1.2 mM and 95% at 0.24 mM	Vibrio sp.
additional information	not inhibitory: ertapenem, meropenem, ampicillin or penicillin G	Vibrio sp.

Organism

Organism	UniProt	Comment	Textmining
Vibrio sp.	Q93P54	-	-
Vibrio sp. G15-21	Q93P54	-	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.044	-	pH 7.0, temperature not specified in the publication	Vibrio sp.	Imipenem

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Release 2023.1 (January 2023)