Literature summary for 3.1.3.1 extracted from

Wada, H.; Yagami, I.; Niwa, N.; Hayakawa, T.; Tsuge, H.
Distribution and properties of rat intestinal alkaline phosphatase isoenzymes (2001), Exp. Anim., 50, 153-158.

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Inhibitors

Inhibitors	Comment	Organism	Structure
L-homoarginine	inhibition of an isozyme from the lower part of intestine	Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
136000	-	x * 136000, isoyzme from the lower part of intestine	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	several intestinal isozymes	-

Reaction

Reaction	Comment	Organism	Reaction ID
a phosphate monoester + H2O = an alcohol + phosphate	Wide specificity. Also catalyses transphosphorylations. Some enzymes hydrolyse diphosphate	Rattus norvegicus	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
intestine	several isozymes, high activity in the upper part compared to the lower one	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.05	3.62	isozymes in intestine segmented into 20 segments, highest activity in the apical part, lowest in the basal, overview	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-nitrophenyl phosphate + H2O	-	Rattus norvegicus	4-nitrophenol + phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 136000, isoyzme from the lower part of intestine	Rattus norvegicus

Synonyms

Synonyms	Comment	Organism
alkaline phosphatase	-	Rattus norvegicus
ALP	-	Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Rattus norvegicus

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Release 2023.1 (January 2023)