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Literature summary for 3.1.21.5 extracted from

  • Ramanathan, S.P.; van Aelst, K.; Sears, A.; Peakman, L.J.; Diffin, F.M.; Szczelkun, M.D.; Seidel, R.
    Type III restriction enzymes communicate in 1D without looping between their target sites (2009), Proc. Natl. Acad. Sci. USA, 106, 1748-1753.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O type III REs require two copies of their asymmetric recognition site in an indirectly repeated, head-to-head orientation cleaving the DNA 25-27 bp downstream of only one of the two sites Escherichia coli specific double-stranded DNA fragments with terminal 5'-phosphate
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Synonyms

Synonyms Comment Organism
EcoP15I
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Escherichia coli
EcoPI
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Escherichia coli
type III RE
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Escherichia coli
type III restriction enzyme
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Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
Escherichia coli
S-adenosyl-L-methionine
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Escherichia coli