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Literature summary for 3.1.21.1 extracted from

  • Dou, Y.; Yang, X.
    Novel high-sensitive fluorescent detection of deoxyribonuclease I based on DNA-templated gold/silver nanoclusters (2013), Anal. Chim. Acta, 784, 53-58.
    View publication on PubMed

Application

Application Comment Organism
analysis use of fluorescent DNA-templated gold/silver nanoclusters as a probe for sensitive detection of deoxyribonuclease I. The procedure is based on quenching fluorescence of DNA-templated gold/silver nanoclusters by DNase I digestion of the DNA 5'-CCCTTAATCCCC-3' template. This decrease in fluorescence intensity permits sensitive detection of DNase I in a linear range of 0.013-60 microg per ml, with a detection limit of 3 ng per ml at a signal-to-noise ratio of 3. The practicality of this probe for detection of DNase I in human serum and saliva samples has been validated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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