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Literature summary for 3.1.21.1 extracted from
- Biological functions of the disulfides in bovine pancreatic deoxyribonuclease (2004), Protein Sci., 13, 875-883.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| C101A | no thioredoxin-like activity as observed for the wild-type | Bos taurus |
| C173A | active | Bos taurus |
| C209A | active | Bos taurus |
| F192C/A217C | active, more heat stable compared to wild-type | Bos taurus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | in the absence of Ca2+, but with Mg2+ the DNase cleaved the substrate DNA in a single nicking mode | Bos taurus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| plasmid DNA + H2O | - |
Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| bovine pancreatic deoxyribonuclease I | - |
Bos taurus |
| bpDNase | - |
Bos taurus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 65 | - |
inactive above 65°C | Bos taurus |
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Release 2023.1 (January 2023)
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