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Literature summary for 3.1.2.22 extracted from

  • Suopanki, J.; Tyynela, J.; Baumann, M.; Haltia, M.
    The expression of palmitoyl-protein thioesterase is developmentally regulated in neural tissues but not in nonneural tissues (1999), Mol. Genet. Metab., 66, 290-293.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus enzyme deficiency causes infantile neuronal ceroid lipofuscinosis, the enzyme plays an important role in the development of the CNS ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Reaction

Reaction Comment Organism Reaction ID
palmitoyl[protein] + H2O = palmitate + protein specific for long-chain thioesters of fatty acids from S-acylated residues in proteins, palmitoyl cysteine and palmitoyl-CoA Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
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cerebellum
-
Rattus norvegicus
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cerebrum
-
Rattus norvegicus
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eye
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Rattus norvegicus
-
additional information the enzyme expression is strictly developmentally regulated in brain and eyes but not in spleen Rattus norvegicus
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neuron
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Rattus norvegicus
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retina
-
Rattus norvegicus
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spleen
-
Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme deficiency causes infantile neuronal ceroid lipofuscinosis, the enzyme plays an important role in the development of the CNS Rattus norvegicus ?
-
?
palmitoyl-[protein] + H2O hydrolysis of long-chain fatty acids from S-acylated proteins and CoA Rattus norvegicus palmitate + protein
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?

Synonyms

Synonyms Comment Organism
Palmitoyl-protein thioesterase
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Rattus norvegicus
PPT
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Rattus norvegicus