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Literature summary for 3.1.11.6 extracted from

  • Thoms, B.; Borchers, I.; Wackernagel, W.
    Effects of single-strand DNases ExoI, RecJ, ExoVII, and SbcCD on homologous recombination of recBCD+ strains of Escherichia coli and roles of SbcB15 and XonA2 ExoI mutant enzymes (2008), J. Bacteriol., 190, 179-192.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information ExoVII, encoded by xseA, has an antirecombination function Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information recJ xseA sbcCD xonA2 quadruple mutants are cold sensitive depending on the xon allele. Absence of the two 3' exonucleases ExoI and ExoVII allows highly efficient conjugational recombination in recBCD+ cells, which is independent of SbcCD, recJ xseA double mutant has lower UV-survival than wild-type Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
single-stranded DNA + H2O
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Escherichia coli hydrolyzed single-stranded DNA
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?

Synonyms

Synonyms Comment Organism
exonuclease VII
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Escherichia coli
ExoVII
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Escherichia coli