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Literature summary for 3.1.1.8 extracted from
- Inhibition of cholinesterases and carboxylesterases of two invertebrate species, Biomphalaria glabrata and Lumbriculus variegatus, by the carbamate pesticide carbaryl (2010), Aquat. Toxicol., 96, 115-123.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-naphthyl methyl carbamate | the effects of sublethal concentrations of 1-naphthyl methyl carbamate on the ChE activities present in the oligochaete Lumbriculus variegatus and in the pigmented Biomphalaria glabrata gastropod are investigated. ChE activity from both species are inhibited, with EC50 and IC50 values 20times lower for the oligochaete than for the gastropod the recovery process in uncontaminated media is more efficient in oligochaetes than in snails. In 2 h the oligochaetes show no inhibition with respect to control values whereas the snails do not reach control values even after 48 h of being in pesticide-free water | Biomphalaria glabrata |  |
| 1-naphthyl methyl carbamate | the effects of sublethal concentrations of 1-naphthyl methyl carbamate on the ChE activities present in the oligochaete Lumbriculus variegatus and in the pigmented Biomphalaria glabrata gastropod are investigated. ChE activity from both species are inhibited, with EC50 and IC50 values 20times lower for the oligochaete than for the gastropod the recovery process in uncontaminated media is more efficient in oligochaetes than in snails. In 2 h the oligochaetes show no inhibition with respect to control values whereas the snails do not reach control values even after 48 h of being in pesticide-free water | Lumbriculus variegatus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Biomphalaria glabrata | - |
- |
- |
| Lumbriculus variegatus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylthiocholine iodide + H2O | - |
Biomphalaria glabrata | ? | - |
? | |
| acetylthiocholine iodide + H2O | - |
Lumbriculus variegatus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ChE | - |
Biomphalaria glabrata |
| ChE | - |
Lumbriculus variegatus |
| cholinesterase | - |
Biomphalaria glabrata |
| cholinesterase | - |
Lumbriculus variegatus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Biomphalaria glabrata |
| 8 | - |
assay at | Lumbriculus variegatus |
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