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Literature summary for 3.1.1.8 extracted from
- Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol (2008), Arch. Biochem. Biophys., 471, 72-76.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| bambuterol | a specific and stereoselective inhibitor of butyrylcholinesterase, which is about 8000times faster inhibited than acetylcholinesterase. Leucine 295 and alanine 337 are crucial residues in BChE for high bambuterol selectivity, preferred inhibition by the R- over the S-bambuterol | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BChE | - |
Mus musculus |
| butyrylcholinesterase | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Mus musculus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | inhibition kinetics | Mus musculus |
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Release 2023.1 (January 2023)
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