Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-methyl, N-alkyl carbamates | inhibition of human BChE by divers derivatives of phenylethylamines and aminoindans is less influenced by the size of the alkyl group and more dependent on the structure of the leaving group, overview | Homo sapiens | |
rivastigmine | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | steady-state kinetics, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylthiocholine + H2O | Homo sapiens | the enzyme might be involved in slowing of neurodegeneration in Alzheimers and Parkinsons diseases, overview | thiocholine + butyrate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylthiocholine + H2O | the enzyme might be involved in slowing of neurodegeneration in Alzheimers and Parkinsons diseases, overview | Homo sapiens | thiocholine + butyrate | - |
? | |
butyrylthiocholine + H2O | substrate as butyrylthiocholine iodide | Homo sapiens | thiocholine + butyrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BChE | - |
Homo sapiens |
butyrylcholinesterase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics, overview | Homo sapiens |