Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-[(methyl[7-[(9-oxo-9H-xanthen-3-yl)oxy]heptyl]amino)methyl]phenyl methylcarbamate | - |
Homo sapiens | |
3-[10-(benzylmethylamino)decyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[11-(benzylmethylamino)undecyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[12-(benzylmethylamino)dodecyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[3-(benzylmethylamino)propoxy]xanthen-9-one | - |
Homo sapiens | |
3-[3-[(2-methoxybenzyl)methylamino]propoxy]-xanthen-9-one | - |
Homo sapiens | |
3-[4-(benzylmethylamino)butoxy]xanthen-9-one | - |
Homo sapiens | |
3-[5-(benzylmethylamino)pentyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[6-(benzylmethylamino)hexyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-(benzylmethylamino)-heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-(benzylmethylamino)heptyloxy]-6-methoxyxanthen-9-one | - |
Homo sapiens | |
3-[7-[(2,3-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2,5-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(2-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(3-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(3-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(4-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[(4-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[ethyl-(2-methoxybenzyl)amino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2,3,4-trimethoxybenzyl)amino]-heptyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2-methylbenzyl)amino]-heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[7-[methyl-(2-nitrobenzyl)amino]heptyloxy]-xanthen-9-one | - |
Homo sapiens | |
3-[8-(benzylmethylamino)octyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[9-(benzylmethylamino)nonyloxy]xanthen-9-one | - |
Homo sapiens | |
3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones | structure-activity relationships, overview, inhibition with high selectivity toward BuChE | Homo sapiens | |
6-[7-(benzylmethylamino)heptyloxy]-2,3-dimethoxyxanthen-9-one | - |
Homo sapiens | |
xanthostigmine | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylthiocholine + H2O | - |
Homo sapiens | thiocholine + butyrate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BuChE | - |
Homo sapiens |
butyrylcholinesterase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00008 | - |
- |
Homo sapiens | 3-[8-(benzylmethylamino)octyloxy]xanthen-9-one | |
0.0001 | - |
- |
Homo sapiens | 3-[9-(benzylmethylamino)nonyloxy]xanthen-9-one | |
0.0001 | - |
- |
Homo sapiens | 3-[10-(benzylmethylamino)decyloxy]xanthen-9-one | |
0.00012 | - |
- |
Homo sapiens | 3-[11-(benzylmethylamino)undecyloxy]xanthen-9-one | |
0.00015 | - |
- |
Homo sapiens | 3-[12-(benzylmethylamino)dodecyloxy]xanthen-9-one | |
0.00032 | - |
- |
Homo sapiens | 3-[7-[ethyl-(2-methoxybenzyl)amino]heptyloxy]-xanthen-9-one | |
0.0008 | - |
- |
Homo sapiens | 3-[7-(benzylmethylamino)-heptyloxy]xanthen-9-one | |
0.00093 | - |
- |
Homo sapiens | 3-[7-[(2-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.001 | - |
- |
Homo sapiens | 3-[7-[methyl-(2,3,4-trimethoxybenzyl)amino]-heptyloxy]xanthen-9-one | |
0.00127 | - |
- |
Homo sapiens | 3-[7-[(2,5-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | |
0.00143 | - |
- |
Homo sapiens | 3-[6-(benzylmethylamino)hexyloxy]xanthen-9-one | |
0.00185 | - |
- |
Homo sapiens | 3-[7-[(3-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.00191 | - |
- |
Homo sapiens | 3-[3-[(2-methoxybenzyl)methylamino]propoxy]-xanthen-9-one | |
0.00201 | - |
- |
Homo sapiens | 3-[7-[(2,3-dimethoxybenzyl)methylamino]heptyloxy]xanthen-9-one | |
0.00211 | - |
- |
Homo sapiens | 3-[7-[(4-methoxybenzyl)methylamino]heptyloxy]-xanthen-9-one | |
0.00249 | - |
- |
Homo sapiens | 3-[5-(benzylmethylamino)pentyloxy]xanthen-9-one | |
0.00265 | - |
- |
Homo sapiens | 3-[4-(benzylmethylamino)butoxy]xanthen-9-one | |
0.00308 | - |
- |
Homo sapiens | 6-[7-(benzylmethylamino)heptyloxy]-2,3-dimethoxyxanthen-9-one | |
0.00833 | - |
- |
Homo sapiens | 3-[3-(benzylmethylamino)propoxy]xanthen-9-one | |
0.014 | - |
- |
Homo sapiens | 3-[7-[methyl-(2-nitrobenzyl)amino]heptyloxy]-xanthen-9-one | |
0.0165 | - |
- |
Homo sapiens | 3-[(methyl[7-[(9-oxo-9H-xanthen-3-yl)oxy]heptyl]amino)methyl]phenyl methylcarbamate | |
0.0295 | - |
- |
Homo sapiens | 3-[7-[methyl-(2-methylbenzyl)amino]-heptyloxy]-xanthen-9-one | |
0.0461 | - |
- |
Homo sapiens | 3-[7-(benzylmethylamino)heptyloxy]-6-methoxyxanthen-9-one | |
0.048 | - |
- |
Homo sapiens | xanthostigmine | |
0.0638 | - |
- |
Homo sapiens | 3-[7-[(3-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | |
0.127 | - |
- |
Homo sapiens | 3-[7-[(4-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one | |
0.269 | - |
- |
Homo sapiens | 3-[7-[(2-chlorobenzyl)methylamino]-heptyloxy]-xanthen-9-one |