Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(trifluoromethyl)phenyl butylcarbamate | - |
Equus caballus | |
2-chlorophenyl butylcarbamate | - |
Equus caballus | |
2-ethylphenyl butylcarbamate | - |
Equus caballus | |
2-methoxyphenyl butylcarbamate | - |
Equus caballus | |
2-methylphenyl butylcarbamate | - |
Equus caballus | |
2-nitrophenyl butylcarbamate | - |
Equus caballus | |
2-tert-butoxyphenyl butylcarbamate | - |
Equus caballus | |
biphenyl-2-yl butylcarbamate | - |
Equus caballus | |
additional information | ortho electron domating substitutents of the inhibitors accelerate inhibition of enzyme by ortho polar effects | Equus caballus | |
phenyl butylcarbamate | - |
Equus caballus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Equus caballus | - |
commercial preparation | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
serum | - |
Equus caballus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butyrylthiocholine + H2O | - |
Equus caballus | butanoate + thiocholine | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0007 | - |
2-nitrophenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 0.04 | Equus caballus | |
0.0017 | - |
2-(trifluoromethyl)phenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 0.11 | Equus caballus | |
0.0042 | - |
2-ethylphenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 0.4 | Equus caballus | |
0.009 | - |
phenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 0.8 | Equus caballus | |
0.011 | - |
biphenyl-2-yl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 1.0 | Equus caballus | |
0.011 | - |
2-methylphenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 1.1 | Equus caballus | |
0.013 | - |
2-chlorophenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 0.6 | Equus caballus | |
0.017 | - |
2-methoxyphenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 2.5 | Equus caballus | |
0.022 | - |
2-tert-butoxyphenyl butylcarbamate | pH 7.0, 25°C, selectivity for EC 3.1.1.8 over EC 3.1.1.7 is 4 | Equus caballus |