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Literature summary for 3.1.1.8 extracted from
- Lizard cholinesterases as biomarkers of pesticide exposure: Enzymological characterization (2002), Environ. Toxicol. Chem., 21, 2319-2325.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dichlorvos | enzyme activity can be restored by incubation with pyridine-2-aldoxime methochloride | Gallotia galloti |  |
| additional information | no substrate inhibition up to 50 mM butyrylthiocholine iodide | Gallotia galloti | |
| paraoxon | enzyme activity can be restored by incubation with pyridine-2-aldoxime methochloride | Gallotia galloti | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1 | - |
butyrylthiocholine iodide | pH 7.6, 25°C | Gallotia galloti | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallotia galloti | - |
lizard | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| butyrylthiocholine iodide + H2O | - |
Gallotia galloti | thiocholine iodide + butyrate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8 | - |
Gallotia galloti |
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