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Literature summary for 3.1.1.7 extracted from

  • SantAnna, M.C.; Soares, V.d.e..M.; Seibt, K.J.; Ghisleni, G.; Rico, E.P.; Rosemberg, D.B.; de Oliveira, J.R.; Schroeder, N.; Bonan, C.D.; Bogo, M.R.
    Iron exposure modifies acetylcholinesterase activity in zebrafish (Danio rerio) tissues: distinct susceptibility of tissues to iron overload (2011), Fish Physiol. Biochem., 37, 573-581.
    View publication on PubMed
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Metals/Ions

Metals/Ions Comment Organism Structure
Iron in vitro, iron promotes a significant increase in AChE activity in brain (52%) and liver (53%) at the higher concentration (2.6 mM). In vivo, a significant increase in enzyme activity is observed in the presence of 15 mg/l in both, brain (62%) and liver tissue (70%) Danio rerio

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetylcholine + H2O Danio rerio
-
 choline + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Danio rerio
-
liver
-
 Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylcholine + H2O
-
 Danio rerio choline + acetate
-
 ?
acetylthiocholine + H2O
-
 Danio rerio thiocholine + acetate
-
 ?

Synonyms

Synonyms Comment Organism
AChE
-
 Danio rerio

Expression

Organism Comment Expression
Danio rerio enzyme transcript levels do not significantly change in the presence of iron additional information