Literature summary for 3.1.1.7 extracted from

Carpinella, M.C.; Andrione, D.G.; Ruiz, G.; Palacios, S.M.
Screening for acetylcholinesterase inhibitory activity in plant extracts from Argentina (2010), Phytother. Res., 24, 259-263.

Search for more literature for 3.1.1.7

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	extracts of Achyrocline tomentosa, Eupatorium viscidum, Ruprechtia apetala, Trichocline reptans, and Zanthoxylum coco present strong inhibition of AChE, higher than 80% at 1 mg/mL. The extracts from Ruprechtia apetala and Trichocline reptans are the most potent, showing complete inhibition of the enzyme with IC50 values 0.0779 and 0.1118 mg/mL, respectively, overview. Acetylcholinesterase inhibitory activity of organic and aqueous fractions obtained from extracts of diverse other plants of central Argentina, overview. IC50 value of Achyrocline tomentosa extract is 0.485 mg/ml, of Eupatorium viscidum is 0.479 mg/ml, and 0.158 mg/ml for extract of Zanthoxylum coco	Electrophorus electricus
physostigmine	92.5% inhibition, IC50 is 0.0028 mg/ml	Electrophorus electricus

Organism

Organism	UniProt	Comment	Textmining
Electrophorus electricus	-	type VI-S enzyme	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Electrophorus electricus	-

Synonyms

Synonyms	Comment	Organism
AChE	-	Electrophorus electricus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
additional information	-	0.0028 mg/ml	Electrophorus electricus	physostigmine

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)