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Literature summary for 3.1.1.7 extracted from

  • Cohen, O.; Kronman, C.; Velan, B.; Shafferman, A.
    Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta) (2004), Biochem. J., 378, 117-128.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.7

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cells Homo sapiens
expressed in HEK-293 cells Bos taurus

General Stability

General Stability Organism
circulatory retention of heterologous AChE in non-human primates is dependent on sialic acid content of the enzyme, AChE without sialic acid residues is rapidly eliminated from the circulation. Homo sapiens
circulatory retention of heterologous AChE in non-human primates is dependent on sialic acid content of the enzyme. AChE without sialic acid residues is rapidly eliminated from the circulation. Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens pivotal role in the cholinergic system, rapid termination of nerve impulse transmission ?
-
 ?
additional information Bos taurus pivotal role in the cholinergic system, rapid termination of nerve impulse transmission ?
-
 ?
additional information Macaca mulatta pivotal role in the cholinergic system, rapid termination of nerve impulse transmission ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Macaca mulatta Q67BC1 exon 2; rhesus macaque
-
Macaca mulatta Q67BC1 exon 3; rhesus macaque
-
Macaca mulatta Q67BC1 exon 4; rhesus macaque
-
Macaca mulatta Q67BC1 exon 6; rhesus macaque
-
Macaca mulatta Q67BC2 exon 5; rhesus macaque
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Macaca mulatta
glycoprotein four N-glycans Bos taurus
glycoprotein three N-glycans Homo sapiens
sialoprotein
-
 Homo sapiens
sialoprotein
-
 Bos taurus
sialoprotein
-
 Macaca mulatta

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylthiocholine + H2O
-
 Homo sapiens thiocholine + acetate
-
 ?
acetylthiocholine + H2O
-
 Bos taurus thiocholine + acetate
-
 ?
acetylthiocholine + H2O
-
 Macaca mulatta thiocholine + acetate
-
 ?
additional information pivotal role in the cholinergic system, rapid termination of nerve impulse transmission Homo sapiens ?
-
 ?
additional information pivotal role in the cholinergic system, rapid termination of nerve impulse transmission Bos taurus ?
-
 ?
additional information pivotal role in the cholinergic system, rapid termination of nerve impulse transmission Macaca mulatta ?
-
 ?