Literature summary for 3.1.1.5 extracted from

Taniyama, Y.; Fuse, H.; Satomi, T.; Tozawa, R.; Yasuhara, Y.; Shimakawa, K.; Shibata, S.; Hattori, M.; Nakata, M.; Taketomi, S.
Loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice (2005), Biochem. Biophys. Res. Commun., 330, 104-110.

Search for more literature for 3.1.1.5

Application

Application	Comment	Organism
medicine	LLPL activity is anti-atherogenic and the regulation of this enzyme might be a novel drug target for the treatment of atherosclerosis	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice. Even in a severe model of atherosclerosis, LCAT-like lysophospholipase exhibits a protective effect on atheroma formation at all stages and throughout the aortic tree in mice fed on normal diet	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice. Even in a severe model of atherosclerosis, LCAT-like lysophospholipase exhibits a protective effect on atheroma formation at all stages and throughout the aortic tree in mice fed on normal diet	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
LCAT-like lysophospholipase	-	Mus musculus
LLPL	-	Mus musculus
lysophospholipase 3	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)