Protein Variants | Comment | Organism |
---|---|---|
C418Y | the mutation abolishes lipoprotein lipases's ability to bind to GPIHBP1 and therefore abolishes LPL transport across endothelial cells byGPIHBP1, without interfering with the enzyme catalytic activity or binding to heparin | Homo sapiens |
E421K | the mutation abolishes lipoprotein lipases's ability to bind to GPIHBP1 and therefore abolishes LPL transport across endothelial cells byGPIHBP1, without interfering with the enzyme catalytic activity or binding to heparin | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
capillary | GPIHBP1 shuttles lipoprotein lipase from subendothelial spaces to the capillary lumen | Homo sapiens | - |
microvascular endothelial cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
triolein + H2O | - |
Homo sapiens | oleate + diolein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LPL | - |
Homo sapiens |